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24th Napa Pain Conference

NPC2017-F05a - Evidence-Based Regenerative Medicine

Aug 18, 2017 10:30am ‐ Aug 18, 2017 12:30pm

Credits: None available.



A review of Juvenile Chondrocytes and the research applications, Platelet Rich Plasma and the different systems that are available, a review on intradiscal biologics, an update on recent Stem Cell Trials.

10:30 Juvenile Chondrocytes & Stem Cells in Cartilage Repair: Jason Dragoo, MD
11:00 Review of PRP Techniques & Applications: Corey W. Hunter, MD
11:30 Intradiscal Biologics & Update on Phase III Intradiscal MSC RCT: Michael J. DePalma, MD
12:00 Autologous Derived Expanded Stem Cells for Osteoarthritis of the Knee: Timothy T. Davis, MD


As a result of completing this course, learners will be able / better able to:

  • Understand the current concepts surrounding the application of Juvenile Chondrocytes as they apply to regenerative medicine.
  • Differentiate between PRP systems and Factor Concentrations.
  • Understand the history of Intradiscal Biologics injections and what therapies are the most promising.
  • Assess the applications of adipose derived stem cells.


  • Lutz, Gregory E. “Increased Nuclear T2 Signal Intensity and Improved Function and Pain in a Patient One Year After an Intradiscal Platelet–Rich Plasma Injection.” Pain Medicine (2017).
  • Dragoo, Jason L. “The Use of Platelet-Rich and Platelet-Poor Plasma to Enhance Differentiation of Skeletal Myoblasts Implications for the Use of Autologous Blood Products for Muscle Regeneration.” Orthopaedic Journal of Sports Medicine 4.7 suppl4 (2016): 2325967116S00150.
  • Taylor, S. E., Lee, J., Smeriglio, P., Razzaque, A., Smith, R. L., Dragoo, J. L., … & Bhutani, N. (2016). Identification of human juvenile chondrocyte-specific factors that stimulate stem cell growth. Tissue Engineering Part A, 22(7-8), 645-653.
  • Tong, Wei, et al. “Cell therapy for the degenerating intervertebral disc.” Translational Research 181 (2017): 49-58.
  • Vedicherla, Srujana, and Conor T. Buckley. “Cell‐based therapies for intervertebral disc and cartilage regeneration—Current concepts, parallels, and perspectives.” Journal of Orthopaedic Research 35.1 (2017): 8-22
  • Noriega, David C., et al. “Intervertebral disc repair by allogeneic mesenchymal bone marrow cells: a randomized controlled trial.” Transplantation (2017).


Category: CME


Credits: None available.

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