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In this study, we compared a non-opioid pharmacologic pain management regimen to a regimen allowing for breakthrough opioids as needed in the postoperative management of patients who underwent elective uncomplicated arthroscopic knee surgery. The non-opioid pain management protocol consisted of oral acetaminophen 650mg q4h x 3 days, gabapentin 300mg TID x 14 days, ketorolac 10mg q6-8h x 5 days, topical lidocaine patch (4%) 1 patch/day x 14 days, and no breakthrough opioids. At two weeks and 6 weeks postoperatively, there were no significant differences in pain scores between the two groups, suggesting non-inferiority of the non-opioid pain management regimen to the traditional approach of postoperative opioid prescription.
