Multidisciplinary pain treatment is effective treatment for chronic pain (You et al., 2021). Since the COVID-19 outbreak, telemedicine has been rapidly adapted and the traditional, in-person multidisciplinary pain programs have been reformatted and adjusted for online programs (Ziadni et al., 2021). However, the effectiveness of the online multidisciplinary pain program and its mechanisms of change remain unknown (Buhrman et al., 2016). Early evidence suggests that the online program may be less effective. To examine its effect and potential mechanisms of change, the current study examined the patient-reported outcomes (PROs) of a zoom-delivered, interactive multidisciplinary pain program, which consisted of psychologists-lead Cognitive Behavioral Therapy (CBT) and physical or occupational therapists-led movement (“CBT and Movement”) programs.