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Mechanisms of Closed-loop SCS

‐ Oct 21, 2021 5:30pm

Mechanisms of Closed-loop SCS: 

5 Years of Patient Data


Join Drs. Eric J. Grigsby, John Parker, and Lawrence Poree for a conversation on closed-loop spinal cord stimulation (SCS). 

  • What are evoked compound action potentials (ECAPs)? 
  • How are they used to create a closed-loop neuromodulation system? 
  • What can continuous monitoring the neural responses tell us about the presence and influence of pharmacological agents? 

This nonaccredited educational webinar is provided for information only.

Additional Resources

  • Brooker, C., Russo, M., Cousins, M. J., Taylor, N., Holford, L., Martin, R., ... & Parker, J. (2021). ECAP‐Controlled Closed‐Loop Spinal Cord Stimulation Efficacy and Opioid Reduction Over 24‐Months: Final Results of the Prospective, Multicenter, Open‐Label Avalon Study. Pain Practice.
  • Heijmans, L., & Joosten, E. A. (2020). Mechanisms and mode of action of spinal cord stimulation in chronic neuropathic pain. Postgraduate medicine, 132(sup3), 17-21.
  • Parker, J., Karantonis, D., & Single, P. (2020). Hypothesis for the mechanism of action of ECAP-controlled closed-loop systems for spinal cord stimulation. Healthcare Technology Letters, 7(3), 76-80.


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