9th Annual Lindahl Lecture
Telomere Maintenance: Chronic Pain in the Context of Premature Aging
As a result of participating in this activity, learners will be able/better able to:
- Monitor signs of premature ageing among chronic pain patients
- Work with patients to mitigate their stress
Telomere length, a measure of cellular aging, is inversely associated with chronic pain severity.
Our curiosity-driven, basic science research was first aimed at understanding, at a molecular level, how cells protect their chromosomal ends (telomeres). Beginning with model organism systems, our subsequent research has led to collaborative discoveries that include understanding of disease processes in humans and optimizing human health.
In this lecture, I briefly explain the fundamental and clinical science discoveries, then discuss the growing evidence that life-long factors impact on telomeres, and may reverberate throughout the life course to affect health. These factors start from earliest life and include nutrition and conditions of pregnancy, and societal and environmental factors. Hence this research has led to broader, including societal, implications.
- Basic science
- Cellular effects of lack of telomere maintenance
- Human genetics
- Causal relationships of telomere maintenance and human diseases
- Human studies
- Correlations - including pain; non-genetic factors influencing telomeres in people
- Interactions of telomere attrition with other factors
- Broader implication
Desirable Physician Attributes
- Medical Knowledge [ACGME/ABMS] about established and evolving biomedical, clinical, and cognate (e.g. epidemiological and social-behavioral) sciences and the application of this knowledge to patient care
- Employ Evidence-based Practice [IOM] Integrate best research with clinical expertise and patient values for optimum care and participate in learning and research activities to the extent feasible
- Patient Care [ACGME/ABMS] Provide care that is compassionate, appropriate and effective for the treatment of health problems and the promotion of health
Accreditation & Designation
Release date: This activity was released 8/27/2021.
Termination date: The content of this activity remains eligible for CME Credit until 8/26/2024, unless reviewed or amended prior to this date.
Neurovations Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Neurovations Education designates this other activity (blended learning) for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Disclosure of Financial Relationships
Neither the presenter, reviewers nor any other person with control of, or responsibility for, the planning, delivery, or evaluation of accredited continuing education has, or has had within the past 24 months, any financial relationship(s) to disclose with ineligible companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.
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9/29/21 2:00 pm