Transforming Personalized Patient Care Through Neuromodulation

Transforming Personalized Patient Care Through Neuromodulation

Outline

An individualized, patient-centered approach for diagnosis and treatment of pain is essential to establishing a therapeutic alliance between patient and clinician. This patient-centered approach needs to focus on achieving improved function, activities of daily living (ADLs), and QOL as well as pain control. 

Solutions for improving management of chronic conditions are under the attention of healthcare systems, due to the increasing prevalence caused by demographic change and better survival, and the relevant impact on healthcare expenditures. Enhancing patients’ actual perception and encouraging self-management and self-awareness can result in a better lifestyle, and improved function for the individual.

As the field of neuromodulation matures, new models give way to better mechanistic understandings, which in turn inform new translational models. This bidirectional relationship between application and understanding leads to broader applications and an ability to tailor therapies to the needs of the individual. 

• Uncovering which mechanisms are essential for treating specific pain conditions and/or patients
• Closed-loop applications
• Developing better translational models
• The clinical value of a new approach to patient care monitoring of functional outcomes
• Low-tech, accessible ways to collect data to drive clinical decision making

Learning Objectives

As a result of participating in this activity, learners will be able/better able to:

• Work with my patients to collect new sources of information about their chronic condition to inform their treatment
• Apply new sources of data to the personalization of care plans tailored to an individual patient's needs

At the Gereau Lab, Dr. Meacham utilizes a multidisciplinary approach, including behavioral studies, electrophysiology, optogenetics, in vivo imaging, molecular and genetic approaches to understand the signaling pathways involved in maladaptive plasticity in the nervous system that underlies pain sensitization.

Electrophysiological recording of neural activity in freely behaving animals, along with optogenetic and chemogenetic modulation of specific cell populations help to understand chronic pain as a disease of circuit dysfunction, and identify therapeutic strategies to normalize this dysfunction to reduce the intensity and impact of pain.

Desirable Physician Attributes

• Patient Care [ACGME/ABMS & IOM] Provide care that is compassionate, appropriate and effective for the treatment of health problems and the promotion of health
• Medical Knowledge [ACGME/ABMS] about established and evolving biomedical, clinical, and cognate (e.g. epidemiological and social-behavioral) sciences and the application of this knowledge to patient care
• Employ Evidence-based Practice [IOM] Integrate best research with clinical expertise and patient values for optimum care and participate in learning and research activities to the extent feasible
• Systems-based practice [ACGME] Awareness and responsiveness to larger context and system of health care, use of system resources

Pain management domains and core competencies

3. Treatment: How is pain safely and effectively treated?

• Monitors the effects of pain management approaches to adjust the plan of care as needed with respect
  to functional outcomes
• Empowers patients to recognize and apply health promotion and self-management strategies

4. Context: How does context affect pain?

• Uses an individualized pain management plan (including risk mitigation) that integrates the perspectives of patients, family and social support systems, and clinicians in the context of available resources

Accreditation & Designation

Release date: This activity was released 8/28/2021.

Termination date: The content of this activity remains eligible for CME Credit until 8/27/2024, unless reviewed or amended prior to this date.

Neurovations Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Neurovations Education designates this other activity (blended learning) for a maximum of 0.50 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosure of Financial Relationships

Neither the presenter, reviewers nor any other person with control of, or responsibility for, the planning, delivery, or evaluation of accredited continuing education has, or has had within the past 24 months, any financial relationship(s) to disclose with ineligible companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

Additional Reading

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